MF5L6 Gene Detail

Summary

• Symbol
  MF5L6
• Name
  modifier of Factor 5 Leiden 6

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:6119616
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 3, Syntenic

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype from multigenic genotypes
  1 phenotype reference
  

• All Mutations and Alleles
  1
• Chemically induced (ENU)
  1
• Find Mice (IMSR)
  0 strains or lines available

Mice heterozygous for this mutation exhibit modifies lethality associated with F5 null Tfpi heterozygous mice.

References

• Summaries
  All 1

  Phenotypes 1
• Earliest
  J:244506 Westrick RJ, et al., Sensitized mutagenesis screen in Factor V Leiden mice identifies thrombosis suppressor loci. Proc Natl Acad Sci U S A. 2017 Sep 05;114(36):9659-9664