Tg(Atoh1-Clrn1)#Kuna
Transgene Detail

Summary

• Symbol: Tg(Atoh1-Clrn1)#Kuna
• Name: transgene insertion, Kumar N Alagramam
• MGI ID: MGI:6156639
• Synonyms: TgAC1
• Transgene: Tg(Atoh1-Clrn1)#Kuna Location: unknown
• Alliance: Tg(Atoh1-Clrn1)#Kuna page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Atoh1-Clrn1)#Kuna expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Clrn1 (MGI:2388124)

• Mutation details: In this construct, the expression of the complete mouse cDNA (including UTRs) in cochlear hair cells is driven by the mouse Atoh1 enhancer and a beta-globin basal promoter. (J:255408)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:255408 Geng R, et al., Modeling and Preventing Progressive Hearing Loss in Usher Syndrome III. Sci Rep. 2017 Oct 18;7(1):13480
• All: 2 reference(s)