Rr57 Other Genome Feature Detail

Summary

• Symbol
  Rr57
• Name
  regulatory region 57
• Synonyms
  HoxD CpG114

• Feature Type
  CpG island
• IDs
  MGI:6195728
• Regulates expression of
  Haglr, Hoxd1 (2 regulated genes)

Location &
Maps

• Sequence Map
  Chr2:74593034-74594216 bp

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 2, Syntenic

Strain
Comparison

• SNPs within 2kb
  95 from dbSNP Build 142

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype reference
  

• All Mutations and Alleles
  2
• Endonuclease-mediated
  2
• Find Mice (IMSR)
  0 strains or lines available

Homozygous deletion or inversion does not show any affect on postnatal weight gain, lethality, or fertility.

References

• Summaries
  All 2

  Phenotypes 1
• Earliest
  J:252916 Zakany J, et al., Control of growth and gut maturation by HoxD genes and the associated lncRNA Haglr. Proc Natl Acad Sci U S A. 2017 Oct 31;114(44):E9290-E9299

Rr57 regulates expression of:

Feature	Feature Type	Location	Reference
Haglr, Hoxd antisense growth associated long non-coding RNA	bidirectional promoter lncRNA gene	Chr2:74578766-74593240 (-)	J:252916
Hoxd1, homeobox D1	protein coding gene	Chr2:74593324-74595486 (+)	J:252916