Tg(Alb-SND1)3aDsar
Transgene Detail

Summary

• Symbol: Tg(Alb-SND1)3aDsar
• Name: transgene insertion 3a, Devanand Sarkar
• MGI ID: MGI:6257844
• Synonyms: Alb/SND1
• Transgene: Tg(Alb-SND1)3aDsar Location: unknown
• Alliance: Tg(Alb-SND1)3aDsar page

Transgene origin

• Strain of Origin: (C57BL/6 x CBA)F1

Transgene description

• Transgene Type: Transgenic (Epitope tag, Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(Alb-SND1)3aDsar expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  SND1 (27044)

  Snd1	(MGI:1929266)

• Mutation details: The C-terminal Myc- and FLAG-tagged human SND1 is under the control of an upstream enhancer region (-10400 to -8500) fused to the 335-bp core region of mouse albumin promoter. Western blot analysis confirmed expression of the protein in liver. Six lines were generated, with line 3a being the highest expressing line. (J:242582)

Disease models

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:242582 Jariwala N, et al., Oncogenic Role of SND1 in Development and Progression of Hepatocellular Carcinoma. Cancer Res. 2017 Jun 15;77(12):3306-3316
• All: 1 reference(s)