Tg(Eno2-Thrsp)#Cheo
Transgene Detail

Summary

• Symbol: Tg(Eno2-Thrsp)#Cheo
• Name: transgene insertion, Jae Hoon Cheong
• MGI ID: MGI:6259176
• Synonyms: THRSP OE
• Transgene: Tg(Eno2-Thrsp)#Cheo Location: unknown
• Alliance: Tg(Eno2-Thrsp)#Cheo page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Eno2-Thrsp)#Cheo expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Thrsp (MGI:109126)

• Mutation details: The mouse Thrsp cDNA is under the control of the neuron-specific enolase promoter. Western blot analysis confirmed overexpression of the transgene in the striatum but not prefrontal cortex. The pound symbol (#) is used when line is not specified and/or lines are pooled. (J:266945)

Disease models

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:266945 Custodio RJP, et al., Overexpression of the Thyroid Hormone-Responsive (THRSP) Gene in the Striatum Leads to the Development of Inattentive-like Phenotype in Mice. Neuroscience. 2018 Oct 15;390:141-150
• All: 2 reference(s)