Gm49948 Gene Detail

Summary

• Symbol
  Gm49948
• Name
  predicted gene, 49948

• Feature Type
  protein coding gene
• IDs
  MGI:6270666
• Alliance
  gene page
• Transcription Start Sites
  13 TSS

Location &
Maps

• Sequence Map
  Chr16:96162994-96326780 bp, + strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 16, Syntenic
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  3870 from dbSNP Build 142
• Strain Annotations
  1

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_6270666	protein coding gene	Chr16:96162994-96326780 (+)
129S1/SvImJ	no annotation
A/J	no annotation
AKR/J	no annotation
BALB/cJ	no annotation
C3H/HeJ	no annotation
C57BL/6NJ	no annotation
CAROLI/EiJ	no annotation
CAST/EiJ	no annotation
CBA/J	no annotation
DBA/2J	no annotation
FVB/NJ	no annotation
LP/J	no annotation
NOD/ShiLtJ	no annotation
NZO/HlLtJ	no annotation
PWK/PhJ	no annotation
SPRET/EiJ	no annotation
WSB/EiJ	no annotation

Homology

• Gene Tree
  Gm49948
  

Human Diseases

• References
  4 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  60 phenotype references
  

• All Mutations and Alleles
  2
• Spontaneous
  1
• Genomic Mutations
  2 involving Gm49948
• Find Mice (IMSR)
  0 strains or lines available

Expression

• Assay Results
  706

Tissue x Stage Matrix

• Other Mouse Links
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  5
• UniProt
  1

• Ensembl
  ENSMUSG00000117081 (Evidence)

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000117081	Ensembl Gene Model | MGI Sequence Detail	163787	C57BL/6J
transcript	ENSMUST00000113795	Ensembl | MGI Sequence Detail	1031	Not Applicable
polypeptide	ENSMUSP00000109426	Ensembl | MGI Sequence Detail	298	Not Applicable

Protein
Information

• UniProt
  1 Sequence
• InterPro Domains
  IPR013151 Immunoglobulin
  IPR036179 Immunoglobulin-like domain superfamily
  IPR013783 Immunoglobulin-like fold
  IPR003599 Immunoglobulin subtype

References

• Summaries
  All 62

  Diseases 4

  Phenotypes 60
• Earliest
  J:42265 Huang TT, et al., Superoxide-mediated cytotoxicity in superoxide dismutase-deficient fetal fibroblasts. Arch Biochem Biophys. 1997 Aug 15;344(2):424-32
• Latest
  J:325522 Urbano-Gamez JD, et al., Prenatal treatment with rapamycin restores enhanced hippocampal mGluR-LTD and mushroom spine size in a Down's syndrome mouse model. Mol Brain. 2021 May 25;14(1):84

TSS for Gm49948:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr139659	Chr16:96162928-96162940 (+)	-60 bp
Tssr139660	Chr16:96162949-96163001 (+)	-19 bp
Tssr139661	Chr16:96163005-96163016 (+)	17 bp
Tssr139662	Chr16:96173776-96173783 (+)	10,786 bp
Tssr139663	Chr16:96173858-96173872 (+)	10,871 bp
Tssr139664	Chr16:96173885-96173908 (+)	10,903 bp
Tssr139665	Chr16:96173909-96173923 (+)	10,922 bp
Tssr139666	Chr16:96174039-96174053 (+)	11,052 bp
Tssr139667	Chr16:96174083-96174105 (+)	11,100 bp
Tssr139668	Chr16:96185098-96185110 (+)	22,110 bp
Tssr139669	Chr16:96187524-96187544 (+)	24,540 bp
Tssr139670	Chr16:96187590-96187600 (+)	24,601 bp
Tssr139671	Chr16:96242426-96242440 (+)	79,439 bp