Tg(CAG-Ptafr)1Tksh
Transgene Detail

Summary

• Symbol: Tg(CAG-Ptafr)1Tksh
• Name: transgene insertion 1, Takao Shimizu
• MGI ID: MGI:6324050
• Synonyms: F055 line, PAFR-Tg
• Transgene: Tg(CAG-Ptafr)1Tksh Location: unknown
• Alliance: Tg(CAG-Ptafr)1Tksh page

Transgene origin

• Strain of Origin: C57BL/6 x DBA/2

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(CAG-Ptafr)1Tksh expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  guinea pig	PTAFR (100720710)

• Mutation details: A transgenic construct expresses a guinea-pig PAFR gene under the control of the a chicken beta actin promotor and the CMV immediate early enhancer. (J:38639)

Disease models

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:38639 Ishii S, et al., Bronchial hyperreactivity, increased endotoxin lethality and melanocytic tumorigenesis in transgenic mice overexpressing platelet-activating factor receptor. EMBO J. 1997 Jan 2;16(1):133-42
• All: 4 reference(s)