Tg(Ace2-ACE2)1Cqin
Transgene Detail

Summary

• Symbol: Tg(Ace2-ACE2)1Cqin
• Name: transgene insertion 1, Chuan Qin
• MGI ID: MGI:6401292
• Synonyms: hACE2
• Transgene: Tg(Ace2-ACE2)1Cqin Location: unknown
• Alliance: Tg(Ace2-ACE2)1Cqin page

Transgene origin

• Strain of Origin: ICR

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(Ace2-ACE2)1Cqin expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  ACE2 (59272)

  Ace2	(MGI:1917258)

• Mutation details: Human ACE2 (hACE2) cDNA upstream of the SV40 poly A tract was placed under the regulatory control of mouse Ace2 promoter sequences (9 kb) derived from BAC RP23-75P20. (J:141460)

Disease models

Expression

In Structures Affected by this Mutation:

18 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:141460 Yang XH, et al., Mice transgenic for human angiotensin-converting enzyme 2 provide a model for SARS coronavirus infection. Comp Med. 2007 Oct;57(5):450-9
• All: 17 reference(s)