Tg(SERPINA1-TAg)1812Jtsb
Transgene Detail

Summary

• Symbol: Tg(SERPINA1-TAg)1812Jtsb
• Name: transgene insertion 1812, Janet S Butel
• MGI ID: MGI:6467540
• Transgene: Tg(SERPINA1-TAg)1812Jtsb Location: unknown
• Alliance: Tg(SERPINA1-TAg)1812Jtsb page

Transgene origin

• Strain of Origin: ICR x (C57BL/6 x C3H)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: The SV40 large tumor antigen (TAg) gene is under the control of the human alpha-1-antitrypsin (SERPINA1) regulatory elements. (J:101633)

Disease models

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:101633 Sepulveda AR, et al., Development of a transgenic mouse system for the analysis of stages in liver carcinogenesis using tissue-specific expression of SV40 large T-antigen controlled by regulatory elements of the human alpha-1-antitrypsin gene. Cancer Res. 1989 Nov 1;49(21):6108-17
• All: 1 reference(s)