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Del(3Dcst1-Dcst2)1Nino Cytogenetic Marker Detail
Summary
  • Symbol
    Del(3Dcst1-Dcst2)1Nino
  • Name
    deletion, Chr3, Naokazu Inoue 1
  • Feature Type
    chromosomal deletion
  • IDs
    MGI:6696425
Location &
Maps
less
  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Genetic Map
    Chromosome 3, Syntenic
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    2 phenotypes from multigenic genotypes
    1 phenotype reference
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit male infertility due to failure of sperm fusion to egg.
References
more
  • Summaries
    All 2
    Phenotypes 1
  • Earliest
    J:304712 Inoue N, et al., Evolutionarily conserved sperm factors, DCST1 and DCST2, are required for gamete fusion. Elife. 2021 Apr 19;10:e66313
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory