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Mirc54 Complex/Cluster/Region Detail
Summary
  • Symbol
    Mirc54
  • Name
    microRNA cluster 54, including Mir379, Mir667, and Mir544
  • Feature Type
    complex/cluster/region
  • IDs
    MGI:6765905
Location &
Maps
less
  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Genetic Map
    Chromosome 12, Syntenic
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotypes from 1 allele in 1 genetic background
    2 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit resistance to diet-induced obesity and hepatic triglyceride accumulation.
References
more
  • Summaries
    All 3
    Phenotypes 2
  • Earliest
    J:308913 Cao C, et al., Maternally expressed miR-379/miR-544 cluster is dispensable for testicular development and spermatogenesis in mice. Mol Reprod Dev. 2018 Mar;85(3):175-177
  • Latest
    J:310890 Cao C, et al., Lack of miR-379/miR-544 Cluster Resists High-Fat Diet-Induced Obesity and Prevents Hepatic Triglyceride Accumulation in Mice. Front Cell Dev Biol. 2021;9:720900
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory