About   Help   FAQ
Cirbil Gene Detail
Summary
  • Symbol
    Cirbil
  • Name
    cardiac injury related BCLAF1-inhibiting lncRNA
  • Synonyms
    lncCIRBIL
Location &
Maps
more
  • Sequence Map
    Chr6:108895915-108915647 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, Syntenic
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    681 from dbSNP Build 142
  • Strain Annotations
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_6828806
 lincRNA gene Chr6:108895783-108915694 (-)
129S1/SvImJ no annotation
A/J no annotation
AKR/J no annotation
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ no annotation
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J no annotation
FVB/NJ no annotation
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    1 phenotype reference
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit increased susceptibility to ischemia/reperfusion injury.
Sequences &
Gene Models
less
  • All Sequences
    6
  • RefSeq
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic 123477722 NCBI Gene Model | MGI Sequence Detail 19733 C57BL/6J ±  kb
transcript NR_173999 RefSeq | MGI Sequence Detail 862 ZRU/MplStud  
For the selected sequence
Other
Accession IDs
less
MGI:7337891
References
more
  • Summaries
    All 6
    Phenotypes 1
  • Earliest
    J:301260 Zhang Y, et al., The long noncoding RNA lncCIRBIL disrupts the nuclear translocation of Bclaf1 alleviating cardiac ischemia-reperfusion injury. Nat Commun. 2021 Jan 22;12(1):522
  • Latest
    J:339952 Jiang Y, et al., Cytoplasmic sequestration of p53 by lncRNA-CIRPILalleviates myocardial ischemia/reperfusion injury. Commun Biol. 2022 Jul 18;5(1):716
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory