Rr127 Other Genome Feature Detail

Summary

• Symbol
  Rr127
• Name
  regulatory region 127
• Synonyms
  Gata2 -77

• Feature Type
  enhancer
• IDs
  MGI:6840235
• Regulates expression of
  Gata2 (1 regulated gene)

Location &
Maps

• Sequence Map
  Chr6:88093936-88094192 bp

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI
• chr6:88116954-88117210 (GRCm38) chr6:88093936-88094192 (GRCm39)

• Genetic Map
  Chromosome 6, Syntenic

Strain
Comparison

• SNPs within 2kb
  114 from dbSNP Build 142

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  3 phenotype references
  

• All Mutations and Alleles
  1
• Targeted
  1
• Find Mice (IMSR)
  0 strains or lines available

References

• Summaries
  All 4

  Phenotypes 3
• Earliest
  J:259078 Johnson KD, et al., Cis-regulatory mechanisms governing stem and progenitor cell transitions. Sci Adv. 2015 Sep;1(8):e1500503
• Latest
  J:303661 You X, et al., Gata2 -77 enhancer regulates adult hematopoietic stem cell survival. Leukemia. 2021 Mar;35(3):901-905

Rr127 regulates expression of:

Feature	Feature Type	Location	Reference
Gata2, GATA binding protein 2	protein coding gene	Chr6:88170873-88184014 (+)	J:259078