Rr150 Other Genome Feature Detail

Summary

• Symbol
  Rr150
• Name
  regulatory region 150
• Synonyms
  Emu, Eu, iEmu

• Feature Type
  enhancer
• IDs
  MGI:6857769
• Cluster Members
  Rr555, Rr148, Rr149 ... (4 members)

Location &
Maps

• Sequence Map
  Chr12:113390871-113391349 bp

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI
• Upstream boundary of enhancer is chr12:113390871 (GRCm39) (next to the downstream boundary of the PCR primer segment used as homology arm to insert a loxP-neo cassette in J:64285 [primers cttgtcGACTTTAGTGTCTTTAATTTCT and acaatcgacctcGAGTTGTAGATCAAGAATG with matching bases capitalized]). Span including J:333306 PCR primers: chr12:113391078-113391349 (GRCm39)

• Genetic Map
  Chromosome 12, Syntenic

Strain
Comparison

• SNPs within 2kb
  68 from dbSNP Build 142

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  4 phenotype references
  

• All Mutations and Alleles
  2
• Targeted
  2
• Find Mice (IMSR)
  0 strains or lines available

References

• Summaries
  All 7

  Phenotypes 4
• Earliest
  J:64285 Gu H, et al., Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting. Cell. 1993 Jun 18;73(6):1155-64
• Latest
  J:342746 Martin OA, et al., The IgH Emicro-MAR regions promote UNG-dependent error-prone repair to optimize somatic hypermutation. Front Immunol. 2023;14:1030813

Rr150 Cluster contains:

More Data for these features

Member	Feature Type	Location
Rr555, regulatory region 555	matrix attachment site	Chr12:113390595-113391026
Rr148, regulatory region 148	enhancer	Chr12:113391013-113391258
Rr149, regulatory region 149	transcription factor binding site	Chr12:113391193-113391206
Rr554, regulatory region 554	matrix attachment site	Chr12:113391243-113391592