Rr158 Other Genome Feature Detail

Summary

• Symbol
  Rr158
• Name
  regulatory region 158
• Synonyms
  Ekappa, iEkappa, Igk-Eik, MiEkappa

• Feature Type
  enhancer
• IDs
  MGI:6860360

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.
• Enhancer is wholly contained on a 740 bp HindIII-AflII restriction fragment (J:32727). Coordinates of restriction sites: chr6:70702935-70702935 (GRCm39).

• Genetic Map
  Chromosome 6, Syntenic

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  8 phenotypes from 4 alleles in 2 genetic backgrounds
  3 phenotypes from multigenic genotypes
  15 phenotype references
  

• All Mutations and Alleles
  4
• Targeted
  4
• Find Mice (IMSR)
  0 strains or lines available

References

• Summaries
  All 18

  Phenotypes 15
• Earliest
  J:12574 Takeda S, et al., Deletion of the immunoglobulin kappa chain intron enhancer abolishes kappa chain gene rearrangement in cis but not lambda chain gene rearrangement in trans. EMBO J. 1993 Jun;12(6):2329-36
• Latest
  J:273872 Barajas-Mora EM, et al., A B-Cell-Specific Enhancer Orchestrates Nuclear Architecture to Generate a Diverse Antigen Receptor Repertoire. Mol Cell. 2019 Jan 3;73(1):48-60.e5