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Rr364729 Other Genome Feature Detail
Summary
  • Symbol
    Rr364729
  • Name
    regulatory region 364729
  • Synonyms
    GAL5.1
  • Feature Type
    enhancer
  • IDs
    MGI:7252951
Location &
Maps
more
  • Sequence Map
    Chr19:3490401-3491799 bp, . strand
    From Ensembl Reg annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • J:334339 sgRNAs: CTCCCTGGAGCAATATGAAG chr19:3490931-3490950 CCCGCTTTCATGGCTCCCAA chr19:3491165-3491184
  • Genetic Map
    Chromosome 19, Syntenic
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    138 from dbSNP Build 142
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    7 phenotypes from 1 allele in 1 genetic background
    2 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous deletion of this Gal enhancer reduces alcohol preference in male and female mice and anxiety-related behavior in males.
Sequences &
Gene Models
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  • All Sequences
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSR00000379511 Ensembl | MGI Sequence Detail 1399 Not Applicable ±  kb
For the selected sequence
Other Database
Links
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Ensembl Regulatory Feature ENSMUSR00000379511
References
more
  • Summaries
    All 3
    Phenotypes 2
  • Earliest
    J:334318 McEwan A, et al., The anxiety and ethanol intake controlling GAL5.1 enhancer is epigenetically modulated by, and controls preference for, high-fat diet. Cell Mol Life Sci. 2021 Mar;78(6):3045-3055
  • Latest
    J:334339 McEwan AR, et al., CRISPR disruption and UK Biobank analysis of a highly conserved polymorphic enhancer suggests a role in male anxiety and ethanol intake. Mol Psychiatry. 2021 Jun;26(6):2263-2276
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory