Rr284 Other Genome Feature Detail

Summary

• Symbol
  Rr284
• Name
  regulatory region 284
• Synonyms
  CRM3, EC1, GCR, HMCO2

• Feature Type
  enhancer
• IDs
  MGI:7346245

Location &
Maps

• Sequence Map
  Chr2:113504419-113505618 bp

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI
• located in Fmn1 intron 13 [in reference to ENSMUST00000081349]

• Genetic Map
  Chromosome 2, Syntenic

Strain
Comparison

• SNPs within 2kb
  101 from dbSNP Build 142

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype from 1 allele in 1 genetic background
  1 phenotype from multigenic genotypes
  1 phenotype reference
  

• All Mutations and Alleles
  2
• Endonuclease-mediated
  2
• Genomic Mutations
  1 involving Rr284
• Find Mice (IMSR)
  0 strains or lines available

References

• Summaries
  All 3

  Phenotypes 1
• Earliest
  J:91385 Zuniga A, et al., Mouse limb deformity mutations disrupt a global control region within the large regulatory landscape required for Gremlin expression. Genes Dev. 2004 Jul 1;18(13):1553-64
• Latest
  J:312378 Malkmus J, et al., Spatial regulation by multiple Gremlin1 enhancers provides digit development with cis-regulatory robustness and evolutionary plasticity. Nat Commun. 2021 Sep 21;12(1):5557