Rr294 Other Genome Feature Detail

Summary

• Symbol
  Rr294
• Name
  regulatory region 294
• Synonyms
  mI12a

• Feature Type
  enhancer
• IDs
  MGI:7356081
• Regulates expression of
  Dlx1, Dlx2 (2 regulated genes)

Location &
Maps

• Sequence Map
  Chr2:71368238-71368773 bp

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI
• J:82853 sequence: chr2:71368238-71368773 (GRCm39)

• Genetic Map
  Chromosome 2, Syntenic

Strain
Comparison

• SNPs within 2kb
  54 from dbSNP Build 142

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  37 phenotype references
  

• All Mutations and Alleles
  1
• Targeted
  1
• Genomic Mutations
  1 involving Rr294
• Find Mice (IMSR)
  0 strains or lines available

References

• Summaries
  All 38

  Phenotypes 37
• Earliest
  J:40427 Qiu M, et al., Role of the Dlx homeobox genes in proximodistal patterning of the branchial arches: mutations of Dlx-1, Dlx-2, and Dlx-1 and -2 alter morphogenesis of proximal skeletal and soft tissue structures derived from the first and second arches. Dev Biol. 1997 May 15;185(2):165-84
• Latest
  J:321980 Su Z, et al., Dlx1/2-dependent expression of Meis2 promotes neuronal fate determination in the mammalian striatum. Development. 2022 Feb 15;149(4):dev200035

Rr294 regulates expression of:

Feature	Feature Type	Location	Reference
Dlx1, distal-less homeobox 1	protein coding gene	Chr2:71358457-71364325 (+)	J:82853
Dlx2, distal-less homeobox 2	protein coding gene	Chr2:71373752-71377095 (-)	J:82853