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Rr295 Other Genome Feature Detail
Summary
  • Symbol
    Rr295
  • Name
    regulatory region 295
  • Synonyms
    Mecp2 Peak-2
  • Feature Type
    enhancer
  • IDs
    MGI:7356631
Location &
Maps
more
  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • J:311942 coordinates flanked by sgRNAs: chrX:71290321-71291474 (NCBIm37) chrX:73088588-73089741 (GRCm39)
  • Genetic Map
    Chromosome X, Syntenic
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 1 allele in 1 genetic background
    1 phenotype reference
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Deletion of this Mcep2 enhancer leads to hyperactivity, increased anxiety and abnormal social behavior.
References
more
  • Summaries
    All 1
    Phenotypes 1
  • Earliest
    J:311942 Shao Y, et al., Identification and characterization of conserved noncoding cis-regulatory elements that impact Mecp2 expression and neurological functions. Genes Dev. 2021 Apr 1;35(7-8):489-494
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory