Rr312 Other Genome Feature Detail

Summary

• Symbol
  Rr312
• Name
  regulatory region 312
• Synonyms
  LCR

• Feature Type
  locus control region
• IDs
  MGI:7378551

Location &
Maps

• Sequence Map
  Chr14:54466135-54471168 bp

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI
• J:330515 ~5kb EcoRI-SmaI fragment containing HS2-6: chr14:54466135-54471168 (GRCm39)

• Genetic Map
  Chromosome 14, Syntenic

Strain
Comparison

• SNPs within 2kb
  186 from dbSNP Build 142

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  3 phenotype references
  

• All Mutations and Alleles
  2
• Endonuclease-mediated
  1
• Targeted
  1
• Genomic Mutations
  1 involving Rr312
• Find Mice (IMSR)
  0 strains or lines available

References

• Summaries
  All 3

  Phenotypes 3
• Earliest
  J:77676 Hong NA, et al., A targeted mutation at the T-cell receptor alpha/delta locus impairs T-cell development and reveals the presence of the nearby antiapoptosis gene Dad1. Mol Cell Biol. 1997 Apr;17(4):2151-7
• Latest
  J:296383 Zhao H, et al., A role of the CTCF binding site at enhancer Ealpha in the dynamic chromatin organization of the Tcra-Tcrd locus. Nucleic Acids Res. 2020 Sep 25;48(17):9621-9636