Tg(KRT14-HPV16E6,HPV16E7)14Kshs
Transgene Detail
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Symbol: |
Tg(KRT14-HPV16E6,HPV16E7)14Kshs |
Name: |
transgene insertion 14, Hans Schreiber |
MGI ID: |
MGI:7397259 |
Synonyms: |
E6/E7LSL |
Transgene: |
Tg(KRT14-HPV16E6,HPV16E7)14Kshs Location: unknown Genetic Position: ChrUN, Syntenic
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Alliance: |
Tg(KRT14-HPV16E6,HPV16E7)14Kshs page
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Transgene Type: |
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Transgenic (Conditional ready, Inserted expressed sequence, Reporter) |
Mutation: |
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Insertion
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Mutation details: The transgenic construct contains the human KRT14 promoter/enhnacer directing expression of a beta globin intron and a loxP-flanked EGFP/STOP, and the E6 and E7 early genes from Human papilloma virus followed by a KRT14 polyA signal. It is estimated that there are about 18 copies of the transgene per homozyous cell. This allele is founder #14.
(J:299115)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:299115 Bottinger P, et al., Cooperation of genes in HPV16 E6/E7-dependent cervicovaginal carcinogenesis trackable by endoscopy and independent of exogenous estrogens or carcinogens. Carcinogenesis. 2020 Nov 13;41(11):1605-1615 |
All: |
1 reference(s) |
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