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Tg(CAG-S100a16)#Gpt
Transgene Detail
Summary
Symbol: Tg(CAG-S100a16)#Gpt
Name: transgene insertion #, GemPharmatech Co., Ltd
MGI ID: MGI:7398506
Synonyms: S100a16TG
Transgene: Tg(CAG-S100a16)#Gpt  Location: unknown  
Alliance: Tg(CAG-S100a16)#Gpt page
Transgene
origin
Strain of Origin:  C57BL/6J
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(CAG-S100a16)#Gpt expresses 1 gene
 
Tg(CAG-S100a16)#Gpt expression driven by 1 gene
    The CAG promoter drives ubiquitous expression of the mouse gene. (J:330793)
Phenotypes
Key:
hm homozygous ht heterozygous tg involves transgenes phenotype observed
cn conditional genotype  cx complex: > 1 genome feature ot other: hemizygous, indeterminate,... N normal phenotype
Genotype/
Background:
Allelic Composition
Genetic Background
Cell Line(s)
 
Phenotypes:
Affected Systems
show or hide all annotated terms
 
homeostasis/metabolism
N
homeostasis/metabolism phenotype
N
liver/biliary system
liver fibrosis
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:330793 Zhang WS, et al., S100a16 deficiency prevents hepatic stellate cells activation and liver fibrosis via inhibiting CXCR4 expression. Metabolism. 2022 Jul 29;135:155271
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory