Rr331 Other Genome Feature Detail

Summary

• Symbol
  Rr331
• Name
  regulatory region 331
• Synonyms
  BENC C

• Feature Type
  enhancer
• IDs
  MGI:7407300

Location &
Maps

• Sequence Map
  Chr15:63519975-63520516 bp

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI
• J:257739: chr15:63479681-63480222 (NCBIm37) chr15:63519975-63520516 (GRCm39)

• Genetic Map
  Chromosome 15, Syntenic

Strain
Comparison

• SNPs within 2kb
  130 from dbSNP Build 142

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  2 phenotypes from multigenic genotypes
  3 phenotype references
  

• All Mutations and Alleles
  8
• Endonuclease-mediated
  1
• Transposon induced
  7
• Genomic Mutations
  7 involving Rr331
• Find Mice (IMSR)
  0 strains or lines available

Deletion of this Myc blood enhancer results in reduced total B cell number.

References

• Summaries
  All 3

  Phenotypes 3
• Earliest
  J:180121 Ruf S, et al., Large-scale analysis of the regulatory architecture of the mouse genome with a transposon-associated sensor. Nat Genet. 2011 Apr;43(4):379-86
• Latest
  J:257739 Bahr C, et al., A Myc enhancer cluster regulates normal and leukaemic haematopoietic stem cell hierarchies. Nature. 2018 Jan 25;553(7689):515-520