Ts(17¹⁶)66Yah Cytogenetic Marker Detail

Summary

• Symbol
  Ts(17¹⁶)66Yah
• Name
  trisomy, Chr 16 translocation to Chr 17, Yann Herault 66

• Feature Type
  unclassified cytogenetic marker
• IDs
  MGI:7408095

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 17, Syntenic

Human Diseases

• Mutations/Alleles
  1 with disease annotations

• References
  1 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  8 phenotypes from multigenic genotypes
  3 phenotype references
  

• All Mutations and Alleles
  1
• Endonuclease-mediated
  1
• Find Mice (IMSR)
  2 strains or lines available

References

• Summaries
  All 3

  Diseases 1

  Phenotypes 3
• Earliest
  J:331897 Duchon A, et al., Ts66Yah, a mouse model of Down syndrome with improved construct and face validity. Dis Model Mech. 2022 Dec 1;15(12):dmm049721
• Latest
  J:351608 Adams AD, et al., Embryonic statistical analyses reveal 2 growth phenotypes in mouse models of Down syndrome. Am J Obstet Gynecol. 2024 Feb;230(2):258.e1-258.e11