Rr337 Other Genome Feature Detail

Summary

• Symbol
  Rr337
• Name
  regulatory region 337
• Synonyms
  Sox9 E160, Sox9 Enh210

• Feature Type
  enhancer
• IDs
  MGI:7413100

Location &
Maps

• Sequence Map
  Chr11:112511718-112512228 bp

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI
• J:332097: chr11:112620892-112621402 (GRCm38) chr11:112511718-112512228 (GRCm39) J:358821: chr11:112482190112483273 (NCBIm37) chr11:112511702-112512785 (GRCm39)

• Genetic Map
  Chromosome 11, Syntenic

Strain
Comparison

• SNPs within 2kb
  155 from dbSNP Build 142

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  2 phenotypes from 1 allele in 1 genetic background
  2 phenotypes from multigenic genotypes
  1 phenotype reference
  

• All Mutations and Alleles
  1
• Endonuclease-mediated
  1
• Find Mice (IMSR)
  0 strains or lines available

Homozygous deletion doesn''t lead to a skeletal phenotype, but double homozygous deletion with Rr592 leads to short tibia and reduced body size.

References

• Summaries
  All 2

  Phenotypes 1
• Earliest
  J:332097 Chen Q, et al., Integration of 3D genome topology and local chromatin features uncovers enhancers underlying craniofacial-specific cartilage defects. Sci Adv. 2022 Nov 25;8(47):eabo3648
• Latest
  J:358821 Ichiyama-Kobayashi S, et al., Chromatin profiling identifies chondrocyte-specific Sox9 enhancers important for skeletal development. JCI Insight. 2024 Jun 10;9(11)