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Swhtr Gene Detail
Summary
  • Symbol
    Swhtr
  • Name
    sweetheart long non-coding RNA
  • Feature Type
    lncRNA gene
  • IDs
    MGI:7464412
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Chromosome: chr17:26,849,907-26,859,715
  • Genetic Map
    Chromosome 17, Syntenic
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    1 phenotype reference
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous null mice show a defect in the hypertrophic response after cardiac injury and increased mortality after myocardial infarction.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    8
  • Tissues
    6
  • cDNA Data
    1
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    Molecular
    Reagents
    less
    • All nucleic 2
      cDNA 1
      Primer pair 1
    References
    more
    • Summaries
      All 2
      Developmental Gene Expression 1
      Phenotypes 1
    • Earliest
      J:342171 Rogala S, et al., The lncRNA Sweetheart regulates compensatory cardiac hypertrophy after myocardial injury in murine males. Nat Commun. 2023 Nov 2;14(1):7024
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    11/12/2024
    MGI 6.24     		The Jackson Laboratory