Del(17Btnl1-Btnl6)1Ahay Cytogenetic Marker Detail

Summary

• Symbol
  Del(17Btnl1-Btnl6)1Ahay
• Name
  deletion, Chr17, Adrian C Hayday 1

• Feature Type
  chromosomal deletion
• IDs
  MGI:7482523

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 17, Syntenic

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype from 1 allele in 1 genetic background
  1 phenotype reference
  

• All Mutations and Alleles
  1
• Endonuclease-mediated
  1
• Find Mice (IMSR)
  0 strains or lines available

Mice homozygous for a deletion of Btnl1, Btnl4, and Btnl6 exhibit a near-ablation of Vgamma7+ intraepithelial T cells.

References

• Summaries
  All 1

  Phenotypes 1
• Earliest
  J:291989 Jandke A, et al., Butyrophilin-like proteins display combinatorial diversity in selecting and maintaining signature intraepithelial gammadelta T cell compartments. Nat Commun. 2020 Jul 28;11(1):3769