Rr485 Other Genome Feature Detail

Summary

• Symbol
  Rr485
• Name
  regulatory region 485
• Synonyms
  Csn SE

• Feature Type
  enhancer
• IDs
  MGI:7664497
• Cluster Members
  Rr486, Rr487, Rr488 ... (4 members)
• Regulates expression of
  Csn1s1, Csn2, Csn1s2a ... (6 regulated genes)

Location &
Maps

• Sequence Map
  Chr5:88017825-88027093 bp

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI
• chr5:88017825-88026873 (GRCm39) chr5:88017825-88027093 (GRCm39) taking into account extend of enhancer E4 deletion

• Genetic Map
  Chromosome 5, Syntenic

Strain
Comparison

• SNPs within 2kb
  446 from dbSNP Build 142

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype reference
  

• All Mutations and Alleles
  2
• Endonuclease-mediated
  2
• Find Mice (IMSR)
  0 strains or lines available

References

• Summaries
  All 2

  Phenotypes 1
• Earliest
  J:341588 Lee HK, et al., Cell-specific and shared regulatory elements control a multigene locus active in mammary and salivary glands. Nat Commun. 2023 Aug 17;14(1):4992

Rr485 regulates expression of:

Feature	Feature Type	Location	Reference
Csn1s1, casein alpha s1	protein coding gene	Chr5:87814067-87830437 (+)	J:341588
Csn2, casein beta	protein coding gene	Chr5:87840478-87847288 (-)	J:341588
Csn1s2a, casein alpha s2-like A	protein coding gene	Chr5:87922426-87936656 (+)	J:341588
Csn1s2b, casein alpha s2-like B	protein coding gene	Chr5:87955980-87972280 (+)	J:341588
Odam, odontogenic, ameloblast asssociated	protein coding gene	Chr5:88032888-88042033 (+)	J:341588
Csn3, casein kappa	protein coding gene	Chr5:88073438-88080409 (+)	J:341588

Rr485 Cluster contains:

More Data for these features

Member	Feature Type	Location
Rr486, regulatory region 486	enhancer	Chr5:88018040-88018488
Rr487, regulatory region 487	enhancer	Chr5:88024456-88025178
Rr488, regulatory region 488	enhancer	Chr5:88025839-88026038
Rr489, regulatory region 489	enhancer	Chr5:88026223-88027093