Rr592 Other Genome Feature Detail

Summary

• Symbol
  Rr592
• Name
  regulatory region 592
• Synonyms
  Sox9 E308

• Feature Type
  enhancer
• IDs
  MGI:7852288

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.
• J:358821: chr11:112334364112335294 (NCBIm37) chr11:112363876-112364806 (GRCm39)

• Genetic Map
  Chromosome 11, Syntenic

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  2 phenotypes from 1 allele in 1 genetic background
  2 phenotypes from multigenic genotypes
  1 phenotype reference
  

• All Mutations and Alleles
  2
• Endonuclease-mediated
  2
• Find Mice (IMSR)
  0 strains or lines available

Homozygous deletion doesn''t lead to a skeletal phenotype, but double homozygous deletion with Rr337 leads to short tibia and reduced body size.

References

• Summaries
  All 2

  Phenotypes 1
• Earliest
  J:358821 Ichiyama-Kobayashi S, et al., Chromatin profiling identifies chondrocyte-specific Sox9 enhancers important for skeletal development. JCI Insight. 2024 Jun 10;9(11)