Rr627 Other Genome Feature Detail

Summary

• Symbol
  Rr627
• Name
  regulatory region 627
• Synonyms
  C1-C4

• Feature Type
  insulator
• IDs
  MGI:8172881
• Cluster Members
  Rr658707, Rr658709, Rr658710 ... (13 members)
• Regulates expression of
  Fgf3, Fgf4 (2 regulated genes)

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.
• chr7:144329467-144353354 (GRCm39)

• Genetic Map
  Chromosome 7, Syntenic

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype reference
  

• All Mutations and Alleles
  2
• Endonuclease-mediated
  2
• Find Mice (IMSR)
  0 strains or lines available

References

• Summaries
  All 2

  Phenotypes 1
• Earliest
  J:361944 Chakraborty S, et al., Deletion of a single CTCF motif at the boundary of a chromatin domain with three FGF genes disrupts gene expression and embryonic development. Dev Cell. 2025 Feb 24;

Rr627 regulates expression of:

Feature	Feature Type	Location	Reference
Fgf3, fibroblast growth factor 3	protein coding gene	Chr7:144392349-144397085 (+)	J:361944
Fgf4, fibroblast growth factor 4	protein coding gene	Chr7:144415123-144418982 (+)	J:361944

Rr627 Cluster contains:

More Data for these features

Member	Feature Type	Location
Rr658707, regulatory region 658707	enhancer	Chr7:144328954-144329569 (.)
Rr658709, regulatory region 658709	CTCF binding site	Chr7:144329993-144330014 (.)
Rr658710, regulatory region 658710	enhancer	Chr7:144333520-144334657 (.)
Rr658711, regulatory region 658711	CTCF binding site	Chr7:144334962-144334983 (.)
Rr658712, regulatory region 658712	enhancer	Chr7:144334970-144335651 (.)
Rr658713, regulatory region 658713	CTCF binding site	Chr7:144335240-144335261 (.)
Rr658714, regulatory region 658714	enhancer	Chr7:144335801-144337084 (.)
Rr658715, regulatory region 658715	enhancer	Chr7:144341707-144344200 (.)
Rr658717, regulatory region 658717	enhancer	Chr7:144346713-144347599 (.)
Rr658718, regulatory region 658718	enhancer	Chr7:144349618-144350657 (.)
Rr658719, regulatory region 658719	enhancer	Chr7:144351073-144351453 (.)
Rr658720, regulatory region 658720	enhancer	Chr7:144352258-144352547 (.)
Rr658721, regulatory region 658721	CTCF binding site	Chr7:144352368-144352389 (.)