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ac Gene Detail
Summary
  • Symbol
    ac
  • Name
    absent corpus callosum
  • Feature Type
    heritable phenotypic marker
  • IDs
    MGI:87865
    NCBI Gene: 11358
  • Alliance
Location &
Maps
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  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Genetic Map
    Chromosome Unknown
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous mice display partial or complete absence of the corpus callosum and also have a tract of fibers, the longitudinal callosal bundle, not present in normal mice.
Sequences &
Gene Models
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Other
Accession IDs
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MGD-MRK-1022
References
more
  • Summaries
    All 8
    Phenotypes 6
  • Earliest
    J:17922 King LS, et al., Absence of Corpus Callosum, a Hereditary Brain Anomaly of the House Mouse. Preliminary Report. Proc Natl Acad Sci U S A. 1932 Aug;18(8):525-8
  • Latest
    J:102685 Schalomon PM, et al., Wheel running behavior is impaired by both surgical section and genetic absence of the mouse corpus callosum. Brain Res Bull. 2002 Jan 1;57(1):27-33

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory