Afr2 Gene Detail

Summary

• Symbol
  Afr2
• Name
  alpha fetoprotein regulation 2, inducibility
• Synonyms
  Afr-2, Rif

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:87953
  NCBI Gene: 110685
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 2, Syntenic
• Mapping Data
  1 experiment

Mutations,
Alleles, and
Phenotypes

Alpha-fetoprotein synthesis is low in adult liver, increasing during liver regeneration. Rate of induction is controlled by Afr2 and varies among inbred strains.

Sequences &
Gene Models

• NCBI Gene
  110685

Other
Accession IDs

MGD-MRK-1175, MGD-MRK-1177, MGD-MRK-13879

References

• Summaries
  All 9
• Earliest
  J:6993 Belayew A, et al., Genetic analysis of alpha-fetoprotein synthesis in mice. Mol Cell Biol. 1982 Nov;2(11):1427-35
• Latest
  J:43375 Jin DK, et al., Genetic mapping of Afr2 (Rif): regulator of gene expression in liver regeneration. Mamm Genome. 1998 Mar;9(3):256-8