ag Gene Detail

Summary

• Symbol
  ag
• Name
  agitans

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:87955
  NCBI Gene: 11592
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 14, Syntenic
• Mapping Data
  1 experiment

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  14 phenotypes from 1 allele in 1 genetic background
  3 phenotype references
  

• All Mutations and Alleles
  1
• Spontaneous
  1
• Find Mice (IMSR)
  0 strains or lines available

Homozygotes mice are characterized by retarded growth, generalized tremor, and ataxia and usually die at weaning, although some live as long as 3 months. Atrophy of the Purkinje cells has been found in some regions of the cerebellum.

Sequences &
Gene Models

• NCBI Gene
  11592

Other
Accession IDs

MGD-MRK-1180

References

• Summaries
  All 4

  Phenotypes 3
• Earliest
  J:266 Hoecker G, et al., Agitans, a new mutation in the house mouse with neurological effects. J Hered. 1954;45:10-14
• Latest
  J:25233 Peters LL, et al., The gene encoding the erythrocyte membrane skeleton protein dematin (Epb4.9) maps to mouse chromosome 14. Genomics. 1995 Apr 10;26(3):634-5