Alm Gene Detail

Summary

• Symbol
  Alm
• Name
  anterior lenticonus with microphthalmia

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:87996
  NCBI Gene: 107785
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome Unknown

Human Diseases

• Diseases
  1 with Alm mouse models

Human Disease

Mouse Models

cataract

IDs

cataract      

DOID:83
ICD10CM:H26
ICD9CM:366.8
OMIM:601371
OMIM:PS116200
UMLS_CUI:C0029531

View 1 model

Mouse Models

Human Disease Modeled: cataract

Allelic Composition	Genetic Background	Reference	Phenotypes
Alm/Alm+	involves: 101 * C3H	J:6686	View

Click on a disease name to see all genes associated with that disease.

• Mutations/Alleles
  1 with disease annotations

• References
  1 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  12 phenotypes from 1 allele in 1 genetic background
  2 phenotype references
  

• All Mutations and Alleles
  1
• Radiation induced
  1
• Find Mice (IMSR)
  0 strains or lines available

Homozygous mutation of this gene results in embryonic lethality. Heterozygous mutants exhibit reduced body size, white belly spot, cataracts, cornea/iris dysmorphology, and microphthalmia.

Sequences &
Gene Models

• NCBI Gene
  107785

Other
Accession IDs

MGD-MRK-1282

References

• Summaries
  All 3

  Diseases 1

  Phenotypes 2
• Earliest
  J:6686 Kratochvilova J, Dominant cataract mutations detected in offspring of gamma-irradiated male mice. J Hered. 1981 Sep-Oct;72(5):302-7
• Latest
  J:9528 Kratochvilova J, et al., Phenotypic characterization and genetic analysis of twenty dominant cataract mutations detected in offspring of irradiated male mice. Genet Res. 1988 Oct;52(2):125-34