alp Gene Detail

Summary

• Symbol
  alp
• Name
  alopecia, recessive

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:88000
  NCBI Gene: 11691
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome Unknown

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  7 phenotypes from 1 allele in 1 genetic background
  1 phenotype reference
  

• All Mutations and Alleles
  1
• Spontaneous
  1
• Find Mice (IMSR)
  0 strains or lines available

Mice with mutations in this gene show hair loss, decreased body weight and increased sensitivity to cold. There is high mortality. Mutant females are unable to nurse their young.

Sequences &
Gene Models

• NCBI Gene
  11691

Other
Accession IDs

MGD-MRK-1287

References

• Summaries
  All 3

  Phenotypes 1
• Earliest
  J:14855 Kobozieff N, et al., Influence de l'alopecie sur quelques caracteristiques biometriques de la souris. Ann Genet Sel Anim. 1970;2:111-17
• Latest
  J:201223 Zhu D, et al., A protective role for FGF-23 in local defence against disrupted arterial wall integrity?. Mol Cell Endocrinol. 2013 Jun 15;372(1-2):1-11