Asp1 QTL Detail

Summary

• Symbol
  Asp1
• Name
  audiogenic seizure prone 1
• Synonyms
  asp-1, Ias

• Feature Type
  QTL
• IDs
  MGI:88085
  NCBI Gene: 11893

Location &
Maps

• Sequence Map
  Chr12:35285496-46801733 bp

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 12, cM position of peak correlated region/marker: Syntenic
• Mapping Data
  6 experiments

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  3 phenotypes from 1 allele in 1 genetic background
  3 phenotype references
  

• All Mutations and Alleles
  1
• Spontaneous
  1
• Find Mice (IMSR)
  0 strains or lines available

Animals homozygous for this allele are susceptible to audiogenic seizures. Seizures are characterized by wild running followed by a clonic seizure and then a fatal tonic seizure.

Sequences &
Gene Models

• NCBI Gene
  11893

Other
Accession IDs

MGD-MRK-11142, MGD-MRK-1422, MGD-MRK-1425

References

• Summaries
  All 9

  Phenotypes 3
• Earliest
  J:6355 Seyfried TN, et al., Genetic analysis of audiogenic seizure susceptibility in C57BL/6J X DBA/2J recombinant inbred strains of mice. Genetics. 1980 Mar;94(3):701-18
• Latest
  J:60516 DiRocco L, et al., Nonallelism for the audiogenic seizure prone (Asp1) and the aryl hydrocarbon receptor (Ahr) loci in mice. J Neurogenet. 1998 Nov;12(4):191-203