Cat3 Gene Detail

Summary

• Symbol
  Cat3
• Name
  dominant cataract 3
• Synonyms
  Cat-3, vacuolated lens with microphthalmia, Vlm

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:88273
  NCBI Gene: 109752
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 10, Syntenic
• Mapping Data
  4 experiments

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  9 phenotypes from 2 alleles in 1 genetic background
  6 phenotype references
  

• All Mutations and Alleles
  3
• Radiation induced
  2
• Spontaneous
  1
• Find Mice (IMSR)
  2 strains or lines available

Homozygotes and heterozygous mutants have cataracts, with vacuoles in their lens, dysplastic irises, small pupils and microphthalmia; some alleles show partial lethality in homozygotes.

Sequences &
Gene Models

• NCBI Gene
  109752

Other
Accession IDs

MGD-MRK-15402, MGD-MRK-1769, MGD-MRK-1771

References

• Summaries
  All 11

  Phenotypes 6
• Earliest
  J:6686 Kratochvilova J, Dominant cataract mutations detected in offspring of gamma-irradiated male mice. J Hered. 1981 Sep-Oct;72(5):302-7
• Latest
  J:53767 Graw J, Cataract mutations and lens development. Prog Retin Eye Res. 1999 Mar;18(2):235-67