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cb Gene Detail
Summary
  • Symbol
    cb
  • Name
    cerebral degeneration
  • Feature Type
    heritable phenotypic marker
  • IDs
    MGI:88277
  • Alliance
    gene page
Location &
Maps
less
  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Genetic Map
    Chromosome Unknown
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    7 phenotypes from 1 allele in 1 genetic background
    1 phenotype reference
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous mutants have cerebral degeneration with visible hydrocephalus at birth affecting primarily the cerebral hemispheres and olfactory lobes, with later involvement of nose and trachea. Most mutants die before maturity.
Other
Accession IDs
less
MGD-MRK-1776
References
more
  • Summaries
    All 2
    Phenotypes 1
  • Earliest
    J:30723 Deol MS, et al., 10.44. A new gene causing cerebral degeneration in the mouse. 1963;1:183-4 (Abstr.)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory