ckr Gene Detail

Summary

• Symbol
  ckr
• Name
  chakragati

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:88414
  NCBI Gene: 12717
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 16, Syntenic
• Mapping Data
  2 experiments

Strain
Comparison

• RFLP
  1

Human Diseases

• Diseases
  1 with ckr mouse models

Human Disease

Mouse Models

schizophrenia

IDs

schizophrenia      

DOID:5419
DOID:14734
ICD10CM:F20
ICD9CM:295
ICD9CM:295.8
ICD9CM:295.80
ICD9CM:295.9
ICD9CM:295.90
MESH:D012559
NCI:C3362
OMIM:181500
UMLS_CUI:C0036341

View 1 model

Mouse Models

Human Disease Modeled: schizophrenia

Allelic Composition	Genetic Background	Reference	Phenotypes
ckr/ckr	involves: C3H/HeRos * C57BL/10Ros	J:87399	View

Click on a disease name to see all genes associated with that disease.

• Mutations/Alleles
  1 with disease annotations

• References
  1 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  12 phenotypes from 1 allele in 1 genetic background
  12 phenotype references
  

• All Mutations and Alleles
  1
• Transgenic
  1
• Find Mice (IMSR)
  0 strains or lines available

Animals homozygous for this mutation exhibit circling behavior almost continuously throughout the night. During daytime, circling behavior is observed in response to stress.

Sequences &
Gene Models

• NCBI Gene
  12717

Molecular
Reagents

• All nucleic 1

  Genomic 1

Other
Accession IDs

MGD-MRK-2004

References

• Summaries
  All 13

  Diseases 1

  Phenotypes 12
• Earliest
  J:10932 Ratty AK, et al., Circling behavior exhibited by a transgenic insertional mutant. Brain Res Mol Brain Res. 1990 Oct;8(4):355-8
• Latest
  J:169719 Dawe GS, et al., Antipsychotic drugs dose-dependently suppress the spontaneous hyperactivity of the chakragati mouse. Neuroscience. 2010 Nov 24;171(1):162-72