cl Gene Detail

Summary

• Symbol
  cl
• Name
  clubfoot

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:88415
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome Unknown

Human Diseases

• Diseases
  1 with cl mouse models

Human Disease

Mouse Models

clubfoot

IDs

clubfoot      

DOID:11836
DOID:0001874
ICD10CM:Q66.89
ICD9CM:754.51
MESH:D003025
NCI:C84641
OMIM:119800
UMLS_CUI:C0009081

View 1 model

Mouse Models

Human Disease Modeled: clubfoot

Allelic Composition	Genetic Background	Reference	Phenotypes
cl/cl	Not Specified	J:294	View

Click on a disease name to see all genes associated with that disease.

• Mutations/Alleles
  1 with disease annotations

• References
  1 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  22 phenotypes from 1 allele in 1 genetic background
  1 phenotype reference
  

• All Mutations and Alleles
  1
• Spontaneous
  1
• Find Mice (IMSR)
  0 strains or lines available

Homozygous mutation of this gene results in reduced viability, reduced growth, and clubbed hindfeet. 59% of mutants die before 14 days of age. Some carpal and tarsal fusion is observed. Mutants have a gummy discharge on the eyes. One or both forefeet mayalso show abnormalities.

Other
Accession IDs

MGD-MRK-2005

References

• Summaries
  All 1

  Diseases 1

  Phenotypes 1
• Earliest
  J:294 Robins MW, A mutation causing congenital clubfoot in the house mouse. J Hered. 1959;50(4):188-192