Coc Gene Detail

Summary

• Symbol
  Coc
• Name
  coralliform cataract

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:88442
  NCBI Gene: 109792
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 16, Syntenic
• Mapping Data
  1 experiment

Human Diseases

• Diseases
  1 with Coc mouse models

Human Disease

Mouse Models

cataract

IDs

cataract      

DOID:83
ICD10CM:H26
ICD9CM:366.8
OMIM:601371
OMIM:PS116200
UMLS_CUI:C0029531

View 2 models

Mouse Models

Human Disease Modeled: cataract

Allelic Composition	Genetic Background	Reference	Phenotypes
Coc/Coc	involves: 101 * C3H * C57BL/6	J:9528	View
Coc/Coc+	involves: 101 * C3H * C57BL/6	J:9528	View

Click on a disease name to see all genes associated with that disease.

• Mutations/Alleles
  1 with disease annotations

• References
  1 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype from 1 allele in 1 genetic background
  2 phenotype references
  

• All Mutations and Alleles
  1
• Radiation induced
  1
• Find Mice (IMSR)
  0 strains or lines available

Heterozygous and homozygous mutants exhibit small spherical opacities in the central part of the lens.

Sequences &
Gene Models

• NCBI Gene
  109792

Other
Accession IDs

MGD-MRK-2046

References

• Summaries
  All 3

  Diseases 1

  Phenotypes 2
• Earliest
  J:9528 Kratochvilova J, et al., Phenotypic characterization and genetic analysis of twenty dominant cataract mutations detected in offspring of irradiated male mice. Genet Res. 1988 Oct;52(2):125-34
• Latest
  J:44211 Sidjanin DJ, et al., Mapping of the autosomal dominant cataract mutation (Coc) on mouse chromosome 16. Invest Ophthalmol Vis Sci. 1997 Nov;38(12):2502-7