Csi QTL Detail

Summary

• Symbol
  Csi
• Name
  corticosteroid side chain isomerase activity

• Feature Type
  QTL
• IDs
  MGI:88536
  NCBI Gene: 110689

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 17, cM position of peak correlated region/marker: Syntenic
• Mapping Data
  3 experiments

Mutations,
Alleles, and
Phenotypes

The level of corticosteroid side-chain isomerase activity in liver is controlled by this locus. BALB/c carry the dominant allele for high isomerase levels (230 pmol/mg protein at 2 h) compared to low activity in C57BL/6 (130 pmol/mg).

Sequences &
Gene Models

• NCBI Gene
  110689

Other
Accession IDs

MGD-MRK-2194

References

• Summaries
  All 3
• Earliest
  J:6936 Walker MC, et al., Genetic control of corticosteroid side-chain isomerase activity in the mouse. Endocrinology. 1983 Mar;112(3):924-30
• Latest
  J:8718 Janat MF, et al., The adrenal X-zone of mice: genetic analysis of its development with recombinant-inbred strains. Exp Biol. 1987;46(4):217-21