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Cyp3a13 Gene Detail
Summary
  • Symbol
    Cyp3a13
  • Name
    cytochrome P450, family 3, subfamily a, polypeptide 13
  • Synonyms
    IIIAm2, steroid inducible
  • Feature Type
    protein coding gene
  • IDs
    MGI:88610
    NCBI Gene: 13113
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:137891194-137919881 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 76.89 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    889 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_88610
 protein coding gene Chr5:137891194-137923872 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030249
 protein coding gene Chr5:142683169-142711847 (-)
A/J MGP_AJ_G0030215
 protein coding gene Chr5:136473130-136501758 (-)
AKR/J MGP_AKRJ_G0030150
 protein coding gene Chr5:140917308-140945990 (-)
BALB/cJ MGP_BALBcJ_G0030227
 protein coding gene Chr5:137860752-137889460 (-)
C3H/HeJ MGP_C3HHeJ_G0029943
 protein coding gene Chr5:141567932-141596641 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030679
 protein coding gene Chr5:147994396-148025909 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027897
 protein coding gene Chr5:130690067-130718496 (-)
CAST/EiJ MGP_CASTEiJ_G0029351
 protein coding gene Chr5:140966164-140996283 (-)
CBA/J MGP_CBAJ_G0029913
 protein coding gene Chr5:153876113-153904736 (-)
DBA/2J MGP_DBA2J_G0030064
 protein coding gene Chr5:136402484-136431148 (-)
FVB/NJ MGP_FVBNJ_G0030019
 protein coding gene Chr5:135564801-135593429 (-)
LP/J MGP_LPJ_G0030153
 protein coding gene Chr5:143194132-143222980 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030051
 protein coding gene Chr5:156687064-156715692 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030720
 protein coding gene Chr5:140763070-140792511 (-)
PWK/PhJ MGP_PWKPhJ_G0029065
 protein coding gene Chr5:135462550-135491643 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028901
 protein coding gene Chr5:138332184-138361876 (-)
WSB/EiJ MGP_WSBEiJ_G0029426
 protein coding gene Chr5:141483359-141512008 (-)



Homology
more
  • Human Ortholog
    CYP3A4, cytochrome P450 family 3 subfamily A member 4
  • Vertebrate Orthologs
    9
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CYP3A4, cytochrome P450 family 3 subfamily A member 4
  • Synonyms
    CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1, VDDR3
  • Links
    NCBI Gene ID: 1576
    neXtProt AC: NX_P08684
    UniProt: P08684

  • Chr Location
    7q22.1; chr7:99756960-99784248 (-)  GRCh38
  • Human Ortholog
    CYP3A5, cytochrome P450 family 3 subfamily A member 5
  • Synonyms
    CP35, CYPIIIA5, P450PCN3, PCN3
  • Links
    NCBI Gene ID: 1577
    neXtProt AC: NX_P20815
    UniProt: P20815

  • Chr Location
    7q22.1; chr7:99648194-99679996 (-)  GRCh38
  • Human Ortholog
    CYP3A7, cytochrome P450 family 3 subfamily A member 7
  • Synonyms
    CP37, CYPIIIA7, P-450111A7, P-450(HFL33), P450-HFLA, P450HLp2
  • Links
    NCBI Gene ID: 1551
    neXtProt AC: NX_P24462
    UniProt: P24462

  • Chr Location
    7q22.1; chr7:99705036-99735196 (-)  GRCh38
  • Human Ortholog
    CYP3A7-CYP3A51P, CYP3A7-CYP3A51P readthrough
  • Synonyms
    CYP3A7, CYP3A7.1L, CYP3A7-3AP1, CYP3A7-CYP3AP1, CYPIIIA7
  • Links
    NCBI Gene ID: 100861540
    neXtProt AC: NX_P24462

  • Chr Location
    7q22.1; chr7:99684677-99735196 (-)  GRCh38
Human Diseases
more
  • Diseases
    5 with human CYP3A4,CYP3A5 associations

Human Disease Mouse Models
      
IDs
IDs
IDs
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    4 phenotypes from multigenic genotypes
    20 phenotype references
Mice homozygous for a knock-out allele show no apparent alterations in hematology, plasma clinical chemistry or pathology.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    32
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    812
  • Tissues
    106
  • cDNA Data
    17
  • Literature Summary
    3
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000029727 Ensembl Gene Model | MGI Sequence Detail 28688 C57BL/6J ±  kb
transcript ENSMUST00000031741 Ensembl | MGI Sequence Detail 2956 Not Applicable  
polypeptide ENSMUSP00000031741 Ensembl | MGI Sequence Detail 503 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 20
    Genomic 2
    cDNA 17
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-2332
References
more
  • Summaries
    All 52
    Developmental Gene Expression 3
    Gene Ontology 8
    Phenotypes 20
  • Earliest
    J:4152 Nelson DR, et al., The P450 superfamily: update on new sequences, gene mapping, accession numbers, early trivial names of enzymes, and nomenclature. DNA Cell Biol. 1993 Jan-Feb;12(1):1-51
  • Latest
    J:337101 Darr J, et al., iTAG-RNA Isolates Cell-Specific Transcriptional Responses to Environmental Stimuli and Identifies an RNA-Based Endocrine Axis. Cell Rep. 2020 Mar 3;30(9):3183-3194.e4
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory