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Mapre1 Gene Detail
Summary
  • Symbol
    Mapre1
  • Name
    microtubule-associated protein, RP/EB family, member 1
  • Synonyms
    5530600P05Rik, BIM1p, D2Ertd459e, Eb1
  • Feature Type
    protein coding gene
  • IDs
    MGI:891995
    NCBI Gene: 13589
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:153583194-153615230 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 75.95 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    796 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_891995
 protein coding gene Chr2:153583131-153615237 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026697
 protein coding gene Chr2:158431447-158465555 (+)
A/J MGP_AJ_G0026663
 protein coding gene Chr2:152063695-152095604 (+)
AKR/J MGP_AKRJ_G0026634
 protein coding gene Chr2:156524254-156556373 (+)
BALB/cJ MGP_BALBcJ_G0026673
 protein coding gene Chr2:152389432-152421961 (+)
C3H/HeJ MGP_C3HHeJ_G0026415
 protein coding gene Chr2:156906074-156942075 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027122
 protein coding gene Chr2:163046046-163081721 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024492
 protein coding gene Chr2:145634580-145665897 (+)
CAST/EiJ MGP_CASTEiJ_G0025876
 protein coding gene Chr2:157170243-157199682 (+)
CBA/J MGP_CBAJ_G0026394
 protein coding gene Chr2:169052758-169094314 (+)
DBA/2J MGP_DBA2J_G0026529
 protein coding gene Chr2:151290452-151322564 (+)
FVB/NJ MGP_FVBNJ_G0026495
 protein coding gene Chr2:149738739-149770733 (+)
LP/J MGP_LPJ_G0026634
 protein coding gene Chr2:158560619-158592266 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026517
 protein coding gene Chr2:173030659-173066552 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027177
 protein coding gene Chr2:156424542-156460115 (+)
PWK/PhJ MGP_PWKPhJ_G0025610
 protein coding gene Chr2:150817211-150849873 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025413
 protein coding gene Chr2:155269240-155302952 (+)
WSB/EiJ MGP_WSBEiJ_G0025946
 protein coding gene Chr2:157325420-157360502 (+)



Homology
more
  • Human Ortholog
    MAPRE1, microtubule associated protein RP/EB family member 1
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MAPRE1, microtubule associated protein RP/EB family member 1
  • Synonyms
    EB1
  • Links
    NCBI Gene ID: 22919
    neXtProt AC: NX_Q15691
    UniProt: Q15691

  • Chr Location
    20q11.21; chr20:32819777-32850405 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    73
  • GO References
    21
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    755
  • Tissues
    48
  • cDNA Data
    25
  • Literature Summary
    7
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000027479 Ensembl Gene Model | MGI Sequence Detail 32037 C57BL/6J ±  kb
transcript ENSMUST00000028981 Ensembl | MGI Sequence Detail 7336 Not Applicable  
polypeptide ENSMUSP00000028981 Ensembl | MGI Sequence Detail 268 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 29
    cDNA 25
    Primer pair 3
    Other 1

    Microarray probesets 10
Other
Accession IDs
less
MGI:1196324, MGI:1918688, MGI:2138969, MGI:2138989, MGI:2139337
References
more
  • Summaries
    All 72
    Developmental Gene Expression 7
    Gene Ontology 21
    Phenotypes 7
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:332434 Xie W, et al., CYLD deubiquitinates plakoglobin to promote Cx43 membrane targeting and gap junction assembly in the heart. Cell Rep. 2022 Dec 27;41(13):111864
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory