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Ppfibp2 Gene Detail
Summary
  • Symbol
    Ppfibp2
  • Name
    PTPRF interacting protein, binding protein 2 (liprin beta 2)
  • Synonyms
    Cclp1, liprin beta 2
  • Feature Type
    protein coding gene
  • IDs
    MGI:894649
    NCBI Gene: 19024
  • Alliance
    gene page
  • Transcription Start Sites
    35 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:107194414-107347790 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 57.21 cM, cytoband F2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    4428 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_894649
 protein coding gene Chr7:107192608-107347790 (+)
129S1/SvImJ MGP_129S1SvImJ_G0032797
 protein coding gene Chr7:110933831-111090011 (+)
A/J MGP_AJ_G0032778
 protein coding gene Chr7:108171342-108334564 (+)
AKR/J MGP_AKRJ_G0032710
 protein coding gene Chr7:110894103-111056460 (+)
BALB/cJ MGP_BALBcJ_G0032784
 protein coding gene Chr7:107878184-108032348 (+)
C3H/HeJ MGP_C3HHeJ_G0032493
 protein coding gene Chr7:110919746-111076449 (+)
C57BL/6NJ MGP_C57BL6NJ_G0033289
 protein coding gene Chr7:115518901-115675063 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030267
 protein coding gene Chr7:109835747-109982879 (+)
CAST/EiJ MGP_CASTEiJ_G0031824
 protein coding gene Chr7:102524355-102682887 (+)
CBA/J MGP_CBAJ_G0032468
 protein coding gene Chr7:119320095-119484679 (+)
DBA/2J MGP_DBA2J_G0032619
 protein coding gene Chr7:106310889-106465369 (+)
FVB/NJ MGP_FVBNJ_G0032571
 protein coding gene Chr7:106163661-106318125 (+)
LP/J MGP_LPJ_G0032711
 protein coding gene Chr7:112523374-112687265 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0032605
 protein coding gene Chr7:120932222-121092924 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0033308
 protein coding gene Chr7:109960634-110118152 (+)
PWK/PhJ MGP_PWKPhJ_G0031530
 protein coding gene Chr7:99184581-99338081 (+)
SPRET/EiJ MGP_SPRETEiJ_G0031380
 protein coding gene Chr7:96548399-96706861 (+)
WSB/EiJ MGP_WSBEiJ_G0031939
 protein coding gene Chr7:110709196-110869460 (+)



Homology
more
  • Human Ortholog
    PPFIBP2, PPFIA binding protein 2
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PPFIBP2, PPFIA binding protein 2
  • Synonyms
    Cclp1
  • Links
    NCBI Gene ID: 8495
    neXtProt AC: NX_Q8ND30
    UniProt: Q8ND30

  • Chr Location
    11p15.4; chr11:7513298-7667304 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotypes from 1 allele in 1 genetic background
    19 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    863
  • Tissues
    36
  • cDNA Data
    101
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000036528 Ensembl Gene Model | MGI Sequence Detail 153377 C57BL/6J ±  kb
    transcript ENSMUST00000098134 Ensembl | MGI Sequence Detail 3827 Not Applicable  
    polypeptide ENSMUSP00000095738 Ensembl | MGI Sequence Detail 904 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 103
      Genomic 1
      cDNA 101
      Primer pair 1

      Microarray probesets 3
    References
    more
    • Summaries
      All 46
      Developmental Gene Expression 2
      Gene Ontology 5
      Phenotypes 19
    • Earliest
      J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory