Dh Gene Detail

Summary

• Symbol
  Dh
• Name
  dominant hemimelia

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:94889
  NCBI Gene: 109698
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 1, Syntenic
• Mapping Data
  14 experiments

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  67 phenotypes from 1 allele in 4 genetic backgrounds
  27 phenotypes from multigenic genotypes
  1 images
  20 phenotype references
  

• All Mutations and Alleles
  1
• Spontaneous
  1
• Find Mice (IMSR)
  1 strains or lines available

Heterozygotes have multiple skeletal abnormalities and lack a spleen. Immune system function is compromised. Some genetic backgrounds result in reduced fertility, urogenital system abnormalities, and compromised autoimmune response. Homozygotes die within a few days of birth.

Sequences &
Gene Models

• NCBI Gene
  109698

Other
Accession IDs

MGD-MRK-8840

References

• Summaries
  All 27

  Phenotypes 20
• Earliest
  J:2484 Truslove GM, Genetical studies on the skeleton of the mouse. V. 'Interfrontal' and 'parted frontals'. J Genet. 1952;51(1):115-122
• Latest
  J:327021 Suto J, Y chromosome of the inbred mouse KK/Ta strain is associated with reduced body size in Y-consomic strains. BMC Res Notes. 2013;6:64