Emv2 Other Genome Feature Detail

Summary

• Symbol
  Emv2
• Name
  endogenous ecotropic MuLV 2
• Synonyms
  Blv-1, Bv-1, Emv-2, Inb-1, N-tropic

• Feature Type
  endogenous retroviral region
• IDs
  MGI:95335
  NCBI Gene: 111372

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 8, Syntenic
• Mapping Data
  23 experiments

Strain
Comparison

• RFLP
  9

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  5 phenotype references
  

• All Mutations and Alleles
  3
• Endonuclease-mediated
  1
• Find Mice (IMSR)
  0 strains or lines available

Mice homozygous for null alleles of Emv2 and Tlr7 fail to exhibit resistance to HSV-2 infection as in Tlr7 null mice.

Sequences &
Gene Models

• NCBI Gene
  111372

Molecular
Reagents

• All nucleic 2

  Genomic 2

Other
Accession IDs

MGD-MRK-11404, MGD-MRK-1580, MGD-MRK-1688, MGD-MRK-9381, MGD-MRK-9441

References

• Summaries
  All 27

  Phenotypes 5
• Earliest
  J:6000 Ihle JN, et al., Genetic analysis of the endogenous C3H murine leukemia virus genome: evidence for one locus unlinked to the endogenous murine leukemia virus genome of C57BL/6 mice. Virology. 1978 Jun 15;87(2):298-306
• Latest
  J:318754 Jayewickreme R, et al., Endogenous Retroviruses Provide Protection Against Vaginal HSV-2 Disease. Front Immunol. 2021;12:758721