epi Gene Detail

Summary

• Symbol
  epi
• Name
  exocrine pancreatic insufficiency

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:95406
  NCBI Gene: 13851
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome Unknown

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  15 phenotypes from 1 allele in 1 genetic background
  5 phenotype references
  

• All Mutations and Alleles
  1
• Spontaneous
  1
• Find Mice (IMSR)
  0 strains or lines available

Mice harboring a spontaneous mutation show perinatal lethality, runting, exocrine pancreas alterations and replacement with adipose tissue, autodigestion of acinar tissue, altered feces composition, neutrophilia, and a reduction in hematocrit, glucose levels and leukocyte and lymphocyte cell number.

Sequences &
Gene Models

• NCBI Gene
  13851

Other
Accession IDs

MGD-MRK-9565

References

• Summaries
  All 6

  Phenotypes 5
• Earliest
  J:5421 Pivetta OH, et al., Exocrine pancreatic insufficiency: a new recessive mutation in mice. J Hered. 1973 Sep-Oct;64(5):301-2
• Latest
  J:5832 Leiter EH, et al., Exocrine pancreatic insufficiency syndrome in CBA/J mice. III. Pathological and genetic analysis. Gastroenterology. 1977 Aug;73(2):260-6