Exz2 QTL Detail

Summary

• Symbol
  Exz2
• Name
  adrenal X zone degeneration 2
• Synonyms
  Exz-2

• Feature Type
  QTL
• IDs
  MGI:95469
  NCBI Gene: 107465

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 12, cM position of peak correlated region/marker: Syntenic
• Mapping Data
  2 experiments

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype from 2 alleles in 1 genetic background
  1 phenotype reference
  

• All Mutations and Alleles
  2
• QTL
  2
• Find Mice (IMSR)
  0 strains or lines available

Exz1 and Exz2 control adrenal X-zone development and involution. BALB/cBy females, carrying the dominant allele, undergo fatty degeneration of the X-zone by 60 days old. Degeneration without lipid accumulation occurs at a later age in C57BL/6By females with the recessive alleles.

Sequences &
Gene Models

• NCBI Gene
  107465

Other
Accession IDs

MGD-MRK-9685, MGD-MRK-9687

References

• Summaries
  All 3

  Phenotypes 1
• Earliest
  J:8718 Janat MF, et al., The adrenal X-zone of mice: genetic analysis of its development with recombinant-inbred strains. Exp Biol. 1987;46(4):217-21