f Gene Detail

Summary

• Symbol
  f
• Name
  flexed-tail

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:95473
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 13, Syntenic
• Mapping Data
  6 experiments

Strain
Comparison

• RFLP
  4

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  28 phenotypes from 1 allele in 3 genetic backgrounds
  6 phenotypes from multigenic genotypes
  26 phenotype references
  

• All Mutations and Alleles
  1
• Spontaneous
  1
• Find Mice (IMSR)
  4 strains or lines available

Homozygous mutants for the spontaneous recessive flexed-tail allele have axial skeletal abnormalities, abnormal heme biosynthesis, and a transient sideroblastic anemia that disappears a few weeks after birth. The tail and belly spot phenotypes have variable penetrance.

Molecular
Reagents

• All nucleic 1

  cDNA 1

References

• Summaries
  All 28

  Phenotypes 26
• Earliest
  J:12951 Hunt HR, et al., Flexed Tail in the Mouse, Mus Musculus. Genetics. 1933 Jul;18(4):335-66
• Latest
  J:151008 Lenox LE, et al., Extramedullary erythropoiesis in the adult liver requires BMP-4/Smad5-dependent signaling. Exp Hematol. 2009 May;37(5):549-58